MOTS-C

For Laboratory Research Use Only — Not for Human or Veterinary Use.

Standard (< 1,000 vials)$240/kit

Volume (1,000+ vials)$160/kit

Quantity (kits)

= 10 vials

Minimum order: 100 vials total. Mix and match across all products.

I confirm this order is for laboratory research use only.For Laboratory Research Use Only — Not for Human or Veterinary Use. By checking this box you affirm this product will not be used for human or animal administration.

Specifications

CAS Number	1627580-64-6
Molecular Formula	C101H152N28O22S2
Molecular Weight	2174.62 g/mol
Purity	≥98% (HPLC)
Form	Lyophilized Powder
Storage	-20°C, desiccated, protected from light
Reconstitution	Bacteriostatic water

Certificate of Analysis

Lot documentation

Every production lot is independently third-party tested. A batch-specific Certificate of Analysis — documenting HPLC purity, mass spectrometry identity confirmation, and net peptide content — is issued with every shipment. View a sample COA to see the format.

View Sample COA About our testing →

Research context

MOTS-c (mitochondrial open reading frame of the 12S rRNA type-c) is a 16-residue mitochondrial-derived peptide encoded within the mitochondrial 12S rRNA region. In vitro and in animal (rodent) models it has been described as interacting with the AMP-activated protein kinase (AMPK) signaling axis and, under metabolic stress, translocating to the nucleus where it has been reported to associate with stress-response transcription-factor pathways such as NRF2/antioxidant-response elements.

Research in isolated cell cultures and rodent models has examined MOTS-c in relation to cellular energy-metabolism pathways, including AMPK activation, folate-methionine cycle intermediates, and expression of glucose-handling genes. Analytical characterization of synthetic MOTS-c preparations has been reported using reversed-phase HPLC for purity assessment and mass spectrometry (ESI-MS and MALDI-TOF) for confirmation of the peptide molecular weight and sequence.

This compound is supplied strictly for in-vitro laboratory research and analytical use. It is not intended for human or veterinary administration, and no statements herein constitute a therapeutic claim or dosing recommendation.